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RFdiffusion — Vecura

RFdiffusion

A generative model of protein backbones for protein binder design.

Job Name

Target Protein (PDB)*

Tip: after uploading, click the preview (eye) button to open the 3D viewer, then click residues to select hotspots.

Target Chain

Upload a target PDB above to choose a chain.

Contigs*

Target chain—

Target range—–

/0chain break — separates the target from the new binder

Binder length–residues sampled by the model

Upload a target PDB above to validate chain ranges (e.g. A114-353).

Hotspot Residues

Upload a target PDB to pick hotspots visually, or type them here (e.g. A56,B20).

Diffusion Steps

steps

Number of Designs

designs

Configure input settings on the left, then click "Run"