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RFantibody — Vecura

RFantibody

Structure-based de novo antibody and nanobody design pipeline combining an antibody-finetuned RFdiffusion for backbone design, ProteinMPNN for CDR sequence design, and an antibody-finetuned RoseTTAFold2 for in silico filtering.

Job Name

Input PDB*

Or load:

Loops to Design*

Sequences per Structure

Sampling Temperature

Omit Amino Acids

Coordinate Noise (augment_eps)

Deterministic Mode

Reproduce identical CDR sequences across runs when enabled.

Configure input settings on the left, then click "Run"